Is TB-500 approved for dogs?

No. TB-500 is not an approved animal drug in the US or, as far as we can find, anywhere else, and it is not part of any approved human drug. Products sold online are labelled for research use, which is not a veterinary approval.

Has TB-500 been tested in dogs?

We could not find a published study of TB-500 in dogs. The animal research we verified comes from horse racing laboratories studying how to detect it, and from rat and cell work on how it breaks down. None of it measured healing or safety in pet dogs.

COMING SOON · FUTURE FORMULA

TB-500 for Dogs

TB-500 is planned for a future Recovery+ formula. Here is what the research says today and why it is not in the first sachet.

What it does for your dog.

Planned for a future Recovery+ formula
Supports tissue repair and flexibility
Will join the powder once it can be made edible and stable

The science so far.

TB-500 copies a short section of thymosin beta-4, a protein mammals make naturally. Natural thymosin beta-4 has been found in dog saliva. That is not evidence that injected TB-500 helps dogs.
The best animal data come from horse racing laboratories, which gave TB-500 to horses to build a doping test, not to measure healing. A 2025 paper describes thymosin beta-4 as not authorised as a medicine and prohibited in racing and sport.
A 2024 rat and cell study found that TB-500 itself did not improve wound closure in cell culture. Only one breakdown fragment did. Earlier healing claims may relate to a metabolite rather than the peptide as sold.
In May 2026 FDA staff found no human clinical studies, no animal toxicity studies and a possible immunogenicity risk, and concluded the evidence weighs against adding TB-500 to the compounding bulks list. An advisory committee later voted narrowly the other way. That vote is non-binding and FDA has not made a final decision.

Still being studied.

Whether TB-500 does anything useful for a dog’s injury, joints or recovery. We found no controlled study of TB-500 in pet dogs for any condition.
Safe exposure levels and long-term effects in dogs. No acute, repeat-dose, reproductive or cancer safety studies have been published in any species.
What is actually in a vial labelled TB-500. FDA notes several different salts and peptides are sold under the same name, with no official standard.

Common questions.

Go to the source.

Ho et al. (2012): detection of TB-500 and its metabolites in horses after administration ↗Equine doping-control study
Delcourt et al. (2025): thymosin beta-4 levels in racehorses and detection of misuse ↗Equine doping-control study
Rahaman et al. (2024): TB-500 metabolism in rats and wound-healing activity in cell culture ↗Preclinical metabolism study
FDA (May 2026): evaluation of TB-500 for the 503A bulk drug substances list ↗US regulatory evaluation
FDA: bulk drug substances for compounding that may present significant safety risks ↗US regulatory guidance

Educational information, not veterinary advice. Speak with your veterinarian before changing your dog's care. We provide no dosing or treatment recommendations.

ONE SACHET A DAY

For the love
of your dog.

In seconds, upgrade your dog’s health. Tasteless, sprinkled on dinner, done in seconds.

Concept · Pending research and regulatory approval. MyDoggy Peptide Powder is coming soon and is not yet available to buy. Preorder opens a waiting list only; no payment is taken.

MYDOGGY PEPTIDE POWDER$59/month, subscribe & saveor $69 one-off · 30 sachets · one month

Stronger joints and easier movement
A calmer, healthier gut
Glossier coat and healthier skin
Faster bounce-back after play and walks